Registry Forge: exposure summary

Invented ALS cohort (demo) · k = 5 · generated 2026-11-13 12:52 UTC
39
Participants with any exposure record
9
Coded records
168
Text candidates

Participants by exposure category

A participant counts once per category. Text candidates include negated and family-history mentions until reviewed.

CategoryParticipants, coded recordParticipants, text candidateParticipants, eitherECTO term
military_serviceheld back for cell size99
not yet assigned
pesticides_agriculture055
not yet assigned
emf_radiation055
not yet assigned
smoking555
ECTO:9000250 exposure to nicotine
head_trauma055
not yet assigned
cyanotoxins055
not yet assigned
solvents_industrial055
not yet assigned

Coded records (ICD-10-CM)

CodeLabelCategoryParticipants
ICD-10-CM Z87.891Personal history of nicotine dependencesmoking5
ICD-10-CM Z91.82Personal history of military deploymentmilitary_serviceheld back for cell size

Text patterns

Context cues come from the words just before each match.

PatternCategoryParticipantsCandidatesShare of candidates with a context cue
smoking_status_former
Former tobacco smoker
smoking516none
pack_years
Pack-years quantification
smoking516none
pesticide_general
Pesticide / herbicide / insecticide exposure
pesticides_agriculture519none
farming_occupation
Agricultural occupation
pesticides_agriculture519none
contact_sport_football
Football history
head_trauma518none
emf_electrical
Electromagnetic field / electrical occupational exposure
emf_radiation516none
cyanotoxin
Cyanotoxin / BMAA exposure
cyanotoxins517none
tce_pce
TCE / PCE chlorinated solvent exposure
solvents_industrial517none
military_service_general
Military service mention
military_service516possible negation 100%
military_gulf_war
Gulf War / OIF / OEF / OND deployment
military_serviceheld back for cell sizeheld back for cell sizeheld back for cell size

ECTO mapping by category

Terms are filled in only where they were checked against an ECTO release; check the others at the EBI Ontology Lookup Service before use.

CategoryECTO termStatusNote
air_pollutionECTO:0000977 exposure to ultrafine respirable suspended particulate matter via inhalationverifiedThis is the verified term for PM2.5/PM10 inhalation. For diesel exhaust, NO2, or other named pollutants, prefer the specific child term.
asbestosECTO:9000033 exposure to asbestosverified
biological_moldnot yet assignedpendingVerify at OLS: fungal toxin / mycotoxin exposure terms.
biological_othernot yet assignedcatch_allCatch-all bucket; not a real ECTO term.
cyanotoxinsnot yet assignedpendingVerify at OLS. ECTO has chemical-level terms for specific cyanotoxins (microcystin, BMAA, anatoxin-a) that may be more appropriate than a generic cyanotoxin parent.
emf_radiationnot yet assignedpendingVerify at OLS: distinguish ionizing radiation (X-ray, gamma) from non-ionizing (EMF, RF, UV). Different ECTO terms.
environmental_othernot yet assignedcatch_allCatch-all bucket; not a real ECTO term. Records here need re-categorization.
head_traumanot yet assignedpendingHead trauma is a physical / mechanical exposure rather than a chemical exposure; ECTO coverage for blast/impact events is limited. May need OBI or another ontology for more precise encoding.
heavy_metalsnot yet assignedpendingNo verified parent term yet. Verified child terms: ECTO:9000945 lead, ECTO:0001571 mercury, ECTO:9000032 arsenic. The individual EXPOSURE_PATTERNS hold these specific IDs in ecto_seed.
military_servicenot yet assignedpendingECTO does not have a "military service" parent term; the operational guidance is to encode specific sub-exposures separately (Agent Orange: herbicide; Camp Lejeune: TCE and PCE in drinking water; blast injury: see head_trauma).
occupational_dustnot yet assignedpendingVerify at OLS: silica, coal, wood, and grain dust each have specific terms.
occupational_noisenot yet assignedpendingVerify at OLS.
occupational_othernot yet assignedcatch_allCatch-all bucket; not a real ECTO term.
other_psychosocialnot yet assignedout_of_scopePsychosocial exposures are out of scope for ECTO; consider other ontologies for these (e.g. OBI, MSH).
pesticides_agriculturenot yet assignedpendingVerify the parent term at OLS (search "exposure to pesticide"). Specific child terms exist for individual agents (paraquat, glyphosate, organophosphates, DDT); prefer the most specific term when the agent is known.
radiationnot yet assignedpendingDistinguish ionizing (medical X-ray, gamma, alpha) vs non-ionizing (UV, RF, EMF); these are different ECTO terms.
smokingECTO:9000250 exposure to nicotineverifiedFor more specific encoding, consider exposure to cigarette smoke, tobacco smoke, or second-hand smoke separately.
soil_pollutionnot yet assignedpendingVerify at OLS.
solvents_industrialnot yet assignedpendingVerify parent term at OLS (search "exposure to organic solvent"). Specific child terms exist for benzene, formaldehyde, TCE/PCE, etc.
water_pollutionnot yet assignedpendingVerify at OLS. Usually co-coded with a specific contaminant (lead in water, TCE in water, etc.).